Cape Girardeau License & Vehicle Registration Office 51 S PLAZA WAYCape Girardeau Missouri 63701 MO USA 51 S PLAZA WAYDirections (573) 335-3659 Monday 08:30 am - 05:30 pm Tuesday 08:30 am - 05:30 pm Wednesday 08:30 am - 05:30 pm Thursday 08:30 am - 05:30 pm Friday 08:30 am - 05:30 pm Saturday Closed Sunday Closed
